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have shown that AMPK activation by AICAR treatment increases MOTS-c levels in skeletal muscle and HEK293 cells 6,8 , and AMPK inhibitor by compound C treatment decreases MOTS-c levels 6

Conclusion In conclusion, the study demonstrated that the addition of l-carnitine enhanced the therapeutic effects of metformin, improving glucose control, reducing depressive behaviors, and ameliorating lipid peroxidation

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doi: 10.1016/j.mehy.2020.110394 130 FerrarottiIOttavianiSBalderacchiAMBarzonVDe SilvestriAPiloniD

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Focus on nutrient-dense meals rich in protein, fiber, and healthy fats, and avoid relying on processed or low-nutrient diet foods that can stall fat loss