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Description

By inhibiting NNMT, 5-Amino-1MQ may spare nicotinamide for NAD+ synthesis via the salvage pathway, thereby activating SIRT1 (Sirtuin 1) pathways associated with mitochondrial biogenesis, fat oxidation, and metabolic flexibility [3]

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doi: 10.1016/j.isci.2024.109784 Roland BC, Lee D, Miller LS, Vegesna A, Yolken R, Severance E, et al

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