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I lost two pant sizes in a short time

On 21 May 2026 , Lilly published the long-awaited topline results from the TRIUMPH-1 Phase 3 trial, and the data is striking: participants on the highest dose lost an average of 28.3% of their body weight at 80 weeks , with 45.3% of patients losing 30% or more a threshold previously only achievable with bariatric surgery

Generic versions remain 5 to 7+ years away, but manufacturer competition and government pressure are driving prices lower faster than the patent timeline alone would suggest

The triple agonist mechanism means appetite suppression builds differently than with dual agonists alone

The closest thing to magic today is a GLP-1, says Dr

Others might prioritize weight loss or cardiovascular protection