Another extensive study detected different post-translationally modified -synuclein in the lysate of red blood cells such as different types of phosphorylated -synuclein apart from pS129, nitrated or glycated or small ubiquitin-like modifier or SUMO-ylated -synuclein, and showed that phosphorylated, nitrated, and glycated -synucleins were elevated and SUMO-ylated -synuclein was decreased in PD patients with respect to that in controls (Miranda et al., 2017)
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