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Maybe [it's] just being younger

At treatment initiation, the median BMI was 34.9 kg/m 2 (IQR: 32.038.6) and the median %EWL was 40.6% (IQR: 27.952.7)

Ca 2+ Imaging We used the membrane permeability indicator Fura-2AM (Dojindo, Kumamoto, Japan) to assess changes in the intracellular Ca 2+ concentration ([Ca 2+ ] i ) of isolated GCs as described previously [15]

This level suits researchers primarily interested in metabolic health improvements like insulin sensitivity and lipid panel normalization, where extreme weight loss is not the primary goal

This may be inconvenient for some patients

Higher-end projections are generally associated with cases involving confirmed, severe diagnoses, repeated emergency care, hospitalization, surgical intervention, or lasting disability, while lower-end projections tend to involve less intensive treatment or shorter symptom duration