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Vitamin b12 holds great safety profile and being a water soluble vitamin, it does not accumulate in body so no chance of toxicity is there

You may become deficient if youre not eating enough foods rich in vitamin B-12, and your body has difficulty absorbing the vitamin because of a lack of intrinsic factors

This occurs when serum levels are high but the B12 isnt being properly taken up by tissues

This is because issues with regular function of the gastrointestinal tract can prevent the proper release and absorption of the vitamin which causes deficiency

Scientific References Kraus D, Yang Q, Kong D, et al

Gut-Brain Axis BPC-157 protects against gastric ulcers and counteracts NSAID-induced gastrointestinal damage