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Removing the "needle barrier" opens the floodgates for a massive segment of the population that isn't particularly fond of syringes
article breaks it down further
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Regulators look closely for compounded versions that basically copy commercial FDA-approved drugs without a clinical need
The practical consequence is that BPC-157 has a cleaner one-name-one-molecule identity, whereas TB-500 is a commercial coinage sitting on top of a more complicated biochemical reality