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When 1 mM of the precursor was supplemented, 15.9 M L-carnitine could be found in the supernatant (1.6% molar yield as judged by the L-carnitine and TML concentrations in the culture medium)

Interestingly, the opioid antagonist naloxone can block some of DSIPs effects, confirming this opioid system involvement

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This guide is written for clinicians who want an accurate, non-hyped understanding of where the DSIP peptide actually stands