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The use of P5091 or P22077, two USP7 inhibitors, display a strong senolytic activity in several models of senescence 31

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Retrieved from Wytiaz, V., Homko, C., Duffy, F., et al

However, GPX4 plays the opposite role in follicular B2 cell development, germinal centre response, and antibody response, which is because B1 and marginal zone B cells are more susceptible to lipid peroxidation and ferroptosis than follicular B2 cells [98]