The physiological function of LP (a) is unclear, but it is considered to be a contributor to atherothrombosis based on its LDL-like properties and its competitive homology to plasminogen (i.e., the precursor of plasmin (EC 3.4.21.7), an enzyme that hydrolyzes fibrin, leading to the dissolution of blood clots) [32-34]
Status: Development NIDA CTN Study lead by T
The condition is diagnosed using the Rotterdam criteria, requiring at least two of three features: irregular menstrual cycles, clinical or biochemical hyperandrogenism (elevated male hormones), and polycystic ovaries visible on ultrasound
Joint Pain & Numbness: Sometimes described as carpal tunnel-like symptoms, this is often a result of fluid retention compressing nerves
Pyke C, Heller RS, Kirk RK, rskov C, Reedtz-Runge S, et al
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