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24,25 Furthermore, this region combines with the Src homology 3 domain to perform its signal transduction function
The Wnt/-Catenin signaling pathway may also mediate the secretion of various growth factors in DPCs (Yu et al., 2020)
For example, the pH-sensitive conjugated micelle system (PAH/RGX-104@PDM/PTX) that encapsulates the hepatic X-nuclear receptor (LXR) agonist RGX-104 and paclitaxel not only has excellent tumor accumulation and tumor penetration but also reduces the level of immunosuppressive MDSCs and significantly reduces tumor immunosuppression, enhances the anti-tumor effect of CTLs thereby inhibiting tumor growth in vivo ( 124)
doi: 10.1016/j.arr.2015.07.008
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