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But a follow-up 2021 study, known as STEP 4, showed that within 48 weeks of no longer taking semaglutide, participants regained approximately two-thirds of their prior weight loss, while those who remained on GLP-1 drug therapy continued to lose weight

In a study of semaglutide efficacy, the average reduction in weight from baseline was 10.2%, but 4.9% of patients achieved over 25% reduction from baseline, and 32.2% achieved less than a 5% reduction from baseline or even weight gain 5

[DOI] [PMC free article] [PubMed] [Google Scholar] 80.Vilsboll T, Christensen M, Junker AE, Knop FK, Gluud LL

For patients, these shifts mean greater convenience and choice

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Urinary creatinine levels were quantified using a mouse creatinine enzymatic assay kit (catalogue no