In the research discussion it is emphasised that a pulsatile signal tends to preserve the natural regulation of the axis rather than continuously flooding the system
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Growth hormone-releasing hormone (GHRH) receptor pathway research
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When glutaminolysis is obstructed, both cystine starvation and erastin treatment fail to trigger ROS accumulation, lipid peroxidation, and subsequent ferroptosis (Gao et al., 2015b