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The decrease in muscle mass was more pronounced in the lower limbs and gynoid compared to the upper limbs and android, which may be related to their higher baseline muscle mass or adaptive changes associated with weight loss, as these areas are major fat depots

[0024] In the present invention, Fmoc-Lys(Alloc)-OH is used as a raw material, which simplifies the deprotection step, and eliminates the side reactions brought out during the deprotection of Mmt and Mtt, and the operation safety risk in removing Dde or ivDde protecting groups in the scale-up process

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