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A broader review found it might brighten skin in sun-exposed areas but labeled the overall evidence as "inconclusive" due to mixed study quality (PubMed Systematic Review)

10.1093/jexbot/53.372.1321 25 Di MascioP.KaiserS.SiesH

8:e2302110.4161/psb.23021 138 UranoJ.NakagawaT.MakiY.MasumuraT.TanakaK.MurataN.et al

Without human trials, clinicians cannot reliably determine appropriate dosing, long-term risks or whether benefits outweigh risks

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