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Whether these actions occur in humans is unclear especially since cessation of GLP-1 therapy rapidly leads to the reappearance of diabetes

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Indication-specific advantages: Glucagon co-agonists such as survodutide, mazdutide, and retatrutide may have superior hepatic effects in MASH and MASLD because glucagon acts directly on liver lipid metabolism

If you notice differences in appetite suppression or side effects after switching, discuss dosage adjustments with your prescriber