In the liver, it neutralises free radicals produced by Phase 1 liver detoxification of chemical toxins
Kuchakulla M, Masterson T, Arora H, Kulandavelu S, Ramasamy R
Enhancement of synaptic plasticity and reversal of impairments in motor and cognitive functions in a mouse model of Angelman Syndrome by a small neurogenic molecule, NSI-189
By repairing gut mucosa, dampening systemic cytokine release, and modulating immune pathways, they help stabilize the gutbrain axisa key regulator of nocturnal comfort and sleep continuity
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Proc Natl Acad Sci USA 104:1662116626 Han J, Cheng FC, Yang Z, Dryhurst G (1999) Inhibitors of mitochondrial respiration, iron (II), and hydroxyl radical evoke release and extracellular hydrolysis of glutathione in rat striatum and substantia nigra: potential implications to Parkinsons disease