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Diabetes Therapy, 15(2), 345357

2 nd ed

MHRA Drug Safety Update

Semaglutide in Patients with Chronic Kidney Disease and Type 2 Diabetes. New England Journal of Medicine , 391(2), 109121

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Also shown are the adverse clinical outcomes associated with elevated systemic TMAO levels in subjects, and enhanced cardiometabolic phenotypes observed with elevated TMAO levels in animal models (46, 12, 13, 1618)