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TB-500 enhances MMP-2 expression to facilitate cellular migration through provisional matrix while stimulating synthesis of ECM components including collagen types I and III, fibronectin, and hyaluronic acid essential for tissue reconstruction

Improvement is progressive across multiple sessions as hair density and follicular plugging reduce

But claiming they "cure hemorrhoids" based on rodent studies and one small case series in a related condition is a significant overreach

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The FDA does not recommend using medications beyond their labeled expiration dates, as the manufacturer cannot guarantee full potency or stability after that point