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These are the points that tend to slow things down later

Molecular & Cellular Biology: Scientists use PEG-MGF in in-vitro assays examining peptide-mediated signaling responses

doi: 10.1056/NEJMoa055222 65

Consistent with these data, GLP-1 attenuated apoptosis of PC12 cells induced by carboxymethyl lysine via peroxisome proliferation activated receptor- (PPAR-) (194)