Citrus: A squeeze of fresh lemon juice in your water or over your fish/chicken
While both are highly effective at improving body composition, they attack fat from completely different biological angles

Effects of Low-Dose, Controlled-Release, Phentermine Plus Topiramate Combination on Weight and Associated Comorbidities in Overweight and Obese Adults (CONQUER): A Randomised, Placebo-Controlled, Phase 3 Trial (April 16, 2011) TOPAMAX (topiramate) TABLETS, for oral use product label (1996) Topiramate (Topamax): Evolving Role in Weight Reduction Management: A Narrative Review (August 31, 2023) Efficacy and Safety of Topiramate in Binge Eating Disorder: A Systematic Review and Meta-analysis (July 9, 2020) Brief Communication: Sleep Curtailment in Healthy Young Men Is Associated with Decreased Leptin Levels, Elevated Ghrelin Levels, and Increased Hunger and Appetite (December 7, 2004) Effects of Chronic Social Stress on Obesity (January 11, 2012) Physical Activity/Exercise and Diabetes: A Position Statement of the American Diabetes Association (October 11, 2016) Severity of Topiramate-Related Working Memory Impairment Is Modulated by Plasma Concentration and Working Memory Capacity (April 16, 2020) Clinical Utility Of Phentermine/Topiramate (Qsymia) Combination For The Treatment Of Obesity (April 08, 2013) Once-Weekly Semaglutide in Adults With Overweight or Obesity (February 10, 2021) Tirzepatide Once Weekly for the Treatment of Obesity (June 4, 2022) OZEMPIC (semaglutide) injection, for subcutaneous use

Patients with contraindications to GLP-1 agonists, including personal or family history of medullary thyroid carcinoma, history of pancreatitis, severe gastroparesis, or pregnancy, should not use either mazdutide or tirzepatide
The discounted GLP-1 net price for state Medicaid programs will be available through additional supplemental rebates (on top of statutory rebates through the MDRP)
They must ensure their products are safe and that label claims are not misleading, but the burden of proving a product is unsafe falls on the FDA, not the manufacturer