Read more about GLP-1 Studies: Tani, Y., Tokuda, M., Nishimoto, N., Yokoi, H., & Izumori, K
Specificity is the key to increased productivity Unlike insulin, LONG R 3 IGF-I specifically targets and activates the type I IGF Receptor (IGF-IR) resulting in greater activation of downstream signaling cascades responsible for proliferation and inhibiting apoptosis
In another study, berberine showed similar results to metformin in improving blood sugar control
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The generally accepted calorie deficit for weight loss is 500-750 calories per day, which typically amounts to 10-15% of calories you burn (sources here and here)
This is a reporting article it covers what has been documented, not what should be done