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Although selenium deficiency, especially if severe, can impact thyroid health, it should be acknowledged that the role of selenium supplementation as a preventive or therapeutic strategy in thyroid diseases is highly controversial

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[13] The current NICE obesity guideline sets out a structured approach involving lifestyle interventions as a first-line measure, licensed pharmacotherapy where clinically appropriate, and bariatric surgery for eligible individuals with severe obesity

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The exact mechanism of peptides acting as antioxidants is not clearly known but some aromatic amino acids and histidine are reported to play an important role in the antioxidant activity

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