Available at: Jastreboff AM, Kaplan LM, Fras JP, Wu Q, Du Y, Gurbuz S, et al
Activation of the transcription factor NRF2 mediates the anti-inflammatory properties of a subset of over-the-counter and prescription NSAIDs
Where the benefit is included, prior authorization is required: BMI 30 or higher, or BMI 27 or higher with a weight-related comorbidity (hypertension, type 2 diabetes, dyslipidemia, or obstructive sleep apnea), plus documented lifestyle program participation and weight-loss maintenance for renewal
Other factors include injection site location (areas with more nerve endings, like the abdomen near the navel, may be more sensitive), skin hydration level, and muscle tension at the injection site
J.WangC.LuoJ
GLP-1 patients in the dataset had an even higher risk if they were younger, male, had smoked in the past, and had a marked decrease in their A1C levels