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Wildtype Kir6.2 and 205-228a mutants were introduced into the intestines of Kir6.2 F/F mice through the Rosa26 - LSL system, similar to the method used for the GCK mutants

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Gaq/11 activation and IP3-mediated calcium mobilization Systemic (Preclinical) Longitudinal bone growth in rodent studies

The expression of NAMPT increased tumor cell proliferation, ERK-1/2 and p38 activity levels, the expression levels of metalloproteases, colony formation, and resistance to apoptosis

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the utility of point-of-care gastric ultrasound in assessing aspiration risk in this population