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Eur Rev Med Pharm Sci

Think of GLP-1s as a powerful accelerator, but you're still in the driver's seat, making those vital daily decisions about what you eat and how you move

From Jan

A few mechanisms that don't reduce neatly to mesolimbic dopamine: (1) conditioned aversion, GLP-1 activation engages nausea/malaise circuits, so some of the reduction in substance use may reflect aversive conditioning rather than reward modulation per se