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Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 10, 513519

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The Role of Genetic Predisposition in Metabolic Risk Documentation Emerging research shows genetic variants in GLP-1 receptor pathways (GLP1R rs6923761), GIPR signaling (GIPR rs1800437), and fat mass regulation (FTO rs9939609, MC4R rs17782313) correlate with weight regulation challenges and insulin resistance patterns

(Singapore: Duke-NUS Medical School) 2239

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The disruption of cellular pathways that results from the production of NAPQI provides a source of potential biomarkers of the severity of the damage