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Likewise, the origin of the glutathione that accumulates in this compartment remains unclear, as does whether external factors, such as glutathione-rich diets or direct intake of this compound as an antioxidant supplement, might influence its levels in the tumour microenvironment

[DOI] [PMC free article] [PubMed] [Google Scholar] 28.McGuire DK, Marx N, Mulvagh SL, Deanfield JE, Inzucchi SE, Pop-Busui R, Mann JFE, Emerson SS, Poulter NR, Engelmann MDM, Ripa MS, Hovingh GK, Brown-Frandsen K, Bain SC, Cavender MA, Gislum M, David JP, Buse JB SOUL Study Group

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Tissue-specific differences in the MASLD-induced effect on GST mRNA/protein expression were observed in MSG male mice, in which renal GSTA1/2 and hepatic GSTM3 expressions were upregulated, while expression of GSTP1/2 was downregulated in the liver and heart (Bousova et al

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