(PubMed) Donin AS, Dent JE, Nightingale CM, et al
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If accompanied by severe abdominal pain, persistent diarrhoea, vomiting, unexplained weight loss, or if symptoms persist beyond 2-4 weeks, it is important to consult a GP for proper evaluation
This genetic foundation enables more confident progression to maximum doses while minimizing unnecessary dose increases and supporting faster achievement of weight loss goals
This is thought to be because its structural similarity with D-fructose means it competes with D-fructose for molecular vehicles that carry sugars into cells in the gut, slowing the rate at which higher-calorie sugars enter the bloodstream, the researchers say
The 50100mg range appears in protocols because it approximates allometric scaling from effective rodent doses, but rigorous human pharmacokinetic data validating those numbers is sparse