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Through a deeper knowledge of the biological function and regulatory mechanism of HO-1, it can provide groundbreaking ideas and strategies for the therapy of diabetic nephropathy

Adequate levels support membrane integrity, structural and enzymatic proteins, as well as the quality of the intracellular environment

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Sci Transl Med (2018) 10(428):eaan8405

Average age of visible signs of onset for vehicle, 25 nmol/kg liraglutide dose animals and 75 nmol/kg liraglutide dosed animals was 68.9 2.7 days, 69.2 2.9 days and 70.1 5.1 days respectively (Fig