Bisphenol-A treatments upregulate the levels of Drp-1 in NSPCs in vitro and in the rat hippocampus, leading to decreased elongated mitochondria, abnormal cristae depletion, apoptosis, and consequently loss of NSPCs proliferation/differentiation balance
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Headache 41 , 629637 (2001)
Unlike traditional medications that might be synthetic or based on larger protein structures, peptides are smaller and can be designed to mimic natural substances in our bodies
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Hepatitis C virus (HCV) infection constitutes a severe public health problem with approximately 80 (64103) million viremic patients worldwide,1 and a natural history leading to liver cirrhosis which entails a risk of hepatocellular carcinoma between 1 and 5% per year.2,3 HCV shows a great genetic variability due to its high replication rate and the reduced capacity of the viral polymerase to correct the errors of the genome that appear during replication