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While semaglutide does not require dose adjustment based on renal function according to FDA labeling, patients with severe gastrointestinal adverse effects may experience dehydration that could impact renal function

Diabetologia 59:25882593 Armstrong MJ, Hull D, Guo K et al (2016) Glucagon-like peptide 1 decreases lipotoxicity in non-alcoholic steatohepatitis

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