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Are compounded GLP-1 medications FDA-approved

Two studies evaluated the effect of exendin on pancreatic gene expression in mice

Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4

Studies use Retatrutide to examine how adding glucagon receptor co-activation to combined GLP-1/GIP agonism further influences energy balance parameters compared to dual-receptor compounds

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Benefits can include: Lower blood pressure Lower total cholesterol Better liver health for those with metabolic dysfunctionassociated steatotic liver disease (MASLD) Lower blood sugar and reduced diabetes risk Lower risk of kidney disease Tirzepatide and orforglipron are newer drugs that dont yet have results from long-term cardiovascular health trials