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GLP-1 medications do not change this calculus

The GLA in evening primrose oil likely interacts with the enzyme

Its that if you think of obesity as a chronic disease and you have all these tools, including GLP-1s, our job is to figure out the best tools with the least side effects, the most safety

Glucagon receptor activation: Increased hepatic glucose output under some conditions, increased energy expenditure, effects on hepatic lipid metabolism

Mechanism: Both reduce appetite and slow gastric emptying

Metabolic and bariatric surgery represents a more definitive intervention for eligible patients with severe obesity who cannot maintain results with pharmacotherapy alone