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Consistently, the mRNA and protein levels of hepatic CYP8B1 were elevated, while the percentage of 12-OH BAs was increased and the proportion of non-12-OH BAs was reduced in the gallbladder bile, ileum, liver, serum, and urine in MMI mice compared to untreated control mice (CT mice) (Supplementary Fig

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Increased levels of both 3-HSD and CYP11A1

10.1111/j.1749-6632.2003.tb07481.x 84 O'BrienL

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