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We cant definitively say that given the methodology used in most studies and 2

Yes, some medications can affect how your body absorbs or uses vitamin B12

Sluming, V., Barrick, T., Howard, M., Cezayirli, E., Mayes, A., & Roberts, N

Metformin increases the body's own production of GLP-1, potentially mimicking some of the effects of GLP-1 receptor agonists

Mitochondrial support Glutathione assists the production of ATP, while also shielding our mitochondria from any potential damage created by free radicals in the energy creation process

It is known that Down patients suffer from mild to moderate oxidative stress due to the overexpression of the Cu-Zn superoxide dismutase (SOD) gene that is also located on chromosome 21 [62]