How Ozempic Works The active ingredient in Ozempic, semaglutide, works by imitating the actions of a hormone called glucagon-like peptide-1 (GLP-1)
However, no large-scale human clinical trials have been completed, so long-term safety data in humans remains limited
13 14 In another study of people who stopped taking semaglutide and didn't receive any dietary or exercise advice, they gained back over two-thirds of the weight
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The results were positive, and the interim analysis of RFS became the final analysis
The absence of a preexisting T2DM diagnosis, the absence of any previous antidiabetic drug, and prescribing outside of the benefit acted as surrogate markers for potential off-label prescribing of the GLP-1 RA brand with the indication of T2DM