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The American Diabetes Association (ADA) Standards of Care support considering GLP-1 receptor agonists, including dual agonists like tirzepatide, early in the treatment algorithm for type 2 diabetes, especially in patients with established cardiovascular disease, chronic kidney disease, or those requiring significant weight reduction
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Stay hydrated and maintain consistent salt intake, as dehydration and electrolyte imbalances amplify fatigue on GLP-1 medications
