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Peptides are chains of amino acids, and these chains occur naturally in the body, yet with the aging process, the body produces fewer peptides

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Strategies to address stability challenges include amino acid modifications, cyclization, and development of protease-resistant sequences

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In 1986, the respective roles of HSL and MGL in TAG hydrolysis were clarified when isolated HSL was found to hydrolyze acylglycerol with an accumulation of MAG in vitro, whereas glycerol release was blunted through selective removal of MGL by immunoprecipitation (31)