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(29) showed the interaction between the level of proinflammatory cytokines and ROS generation in the model of gastric ischemia-reperfusion and concluded that a decrease of ROS production caused the inhibition of adhesion molecules expression, leads to the decrease of mucosal neutrophil infiltration

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Some inherent mechanisms of the tumor itself help tumor cells escape the surveillance and killing effects of the immune system, so tumor immune escape is also one of the bottlenecks to improving the current therapeutic effect on tumors (138)