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Herbal remedies have been part of many civilizations for millennia, with the first known use in India and China 5000 years ago

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To obtain global insights into cellular plasticity in response to IF and in dependence of adipocyte p53 status, we performed single nuclei RNA sequencing (snRNA-seq) on eWAT of HFD-AL, HFD-IF, and HFD-IF-KO mice

while multiple metabolites trended in the same direction between CR and DL-fed mice, the only significantly altered metabolite that was shared in both CR and DL-fed mice was glucose-6-phosphate, which was decreased in the plasma of both groups (Figs

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