Frequency of relapse over time based on baseline stage in esophageal cancer patients treated with definitive chemoradiation (DCRT)
Given the essential role of mitochondrial GSH import by SLC25A39/40 in proliferation, we predict that mitochondrial GSH depletion should further sensitize cells to a decrease in cellular GSH availability
Key takeaways: The GST family of genes encodes eight different enzymes that combine with glutathione in the elimination of many different environmental toxins
Am J Clin Dermatol
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Br J Pharmacol 155:185197 Ren SX, Shen J, Cheng AS, Lu L, Chan RL, Li ZJ, Wang XJ, Wong CC, Zhang L et al (2013) FK-16 derived from the anticancer peptide LL-37 induces caspase-independent apoptosis and autophagic cell death in colon cancer cells