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Endothelial cells line the inner layer of blood vessels that keep micro- and macro-vascular health by sensing pathogen/danger signals and secreting vasoactive (e.g., vasorelaxing and vasoconstricting) molecules and are essential for maintaining tissue homeostasis (23, 87)

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The Impact of GLP-1 on the Balance between Bone Formation and Bone Resorption Normal bone metabolism in humans involves both bone formation and bone resorption in a balanced state of equilibrium