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Comirnaty (tozinameran) Disease area(s): Vaccines/infectious diseases Manufacturer(s): Pfizer/BioNTech 2024 Sales (USD ): $7.79 billion Why it sold so well: In 2024, Pfizers COVID-19 vaccine, Comirnaty, generated $3.38 billion in revenue during the fourth quarter, surpassing expectations by approximately $280 million, and $5.35 billion for the year