Pregnancy stretch marks require targeted treatments such as fractional CO2 laser, MNRF, and TCA cross for deeper indented marks
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Mechanistically, these agents activate the Nrf2/ARE, NF-B, MAPK, PI3K/Akt/mTOR, and SIRT1/PGC-1 pathways, protect mitochondria and the bloodnerve barrier, and upregulate endogenous antioxidant enzymes
Advantages Enhanced Metabolism
NF-B in oxidative stress
Cersosimo, E., Johnson, E