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One challenge when validating a pre-established, generic HRQoL instrument for use in a specific disease population is in the identification of appropriate measures against which to test the instrument (construct validity), when no gold standard is available (criterion validity)

Ann Clin Biochem 34(3):319320 Piggott AM, Karuso P (2007) Fluorometric assay for the determination of glutathione reductase activity

Poor sleep and less energy often precipitate a slowing of the metabolic processes, which can, in turn, lead to weight gain after undergoing a hysterectomy

Output above 3 liters daily, or urinary frequency every 30 to 60 minutes, is excessive and warrants evaluation

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Its not a finished story, and its not meant for anything beyond controlled lab work, but thats exactly what makes it worth studying further