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Addiction medicine currently treats substances individually, a nicotine patch for smoking, and naltrexone for alcohol, with limited crossover between approaches

Side effects and safety Like other incretin-based medicines, the most common side effects are gastrointestinal : nausea, diarrhoea, constipation and occasional vomitingusually milder with gradual dose increases and care around trigger foods (rich, spicy or very large meals)

These medications work by mimicking endogenous GLP-1, an incretin hormone that plays crucial roles in glucose homeostasis and appetite regulation

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A high sodium intake can also increase oxidative stress in the kidneys, further exacerbating kidney issues

In addition to its glucose-lowering effects, semaglutide has also shown benefits in terms of weight loss