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Evidence from systematic reviews of medication adherence indicates that convenience is highly individual, underscoring the importance of selecting a routine that is sustainable over time

The primary concern, especially for those taking GLP-1s for weight management, is the very real risk of regaining any weight youve lost while on the medication

In consideration of the dual roles of GLP-1RAs in hypoglycemic effects and preventing CVD among T2DM patients, we reviewed the cardiovascular effects and molecular mechanisms of GLP-1RAs in CVOTs, animal models and cultured cells, and discuss how these findings transform pharmacotherapies for T2DM, and even expand the indication of this important category of anti-diabetic drugs to CVD patients without diabetes

Cardiometabolic risk factors, such as C-reactive protein, lipids, and blood pressure, were also reduced with semaglutide treatment compared with placebo [49]