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The variant involved in C677T is a change from Cytosine (C) to Thymine (T) at position 677

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Upon amino acid deprivation, it is established that uncharged transfer RNAs (tRNAs) triggers an adaptive integrated stress response, termed amino acid response (AAR), which activates the expression of stress-responsive transcription factor ATF4 45,46

Available at 10mg, is a synthetic research peptide commonly investigated in laboratory studies involving peptide signalling pathways, cellular biology models, and peptide-protein interactions