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Perivascular inflammation in pulmonary arterial hypertension

Med 112, 433444 [DOI] [PubMed] [Google Scholar] 110.High KA and Roncarolo MG (2019) Gene Therapy

Given the excellent antimicrobial performance of NO and its synergistic effect with other antibacterial agents, many researchers have exploited its antibacterial potential in the treatment of bacterial infections in diabetic wound healing

Throughout this article, receptor subtypes defined from cloned genes are referred to as D 1 , D 2 , D 3 , D 4 , D 5 , and where only the subfamily of receptor has been defined pharmacologically the terms used are the D 1 -like and D 2 -like nomenclature

This complexity arises from multifactorial interactions, catalytic degradation kinetics, the hook effect, and tissue-specific E3 ligase expression, that decouple plasma concentration from pharmacological effect